Scripps scientists work to create vaccine against cocaine addiction

By City News Service

The common cold virus might be good for something, after all, with scientists at the La Jolla-based The Scripps Research Institute using part of it to develop a vaccine against cocaine addiction.

TSRI Professor Kim Janda combined a chemically modified cocaine antigen — a substance that stimulates the production of antibodies — with adenovirus, which causes the common cold, to create an immune response against the illegal drug, according to the institute.

Working in conjunction with Cornell University and Weill Cornell Medical College, Janda found the new treatment to be successful in experiments in test tubes and laboratory mice for three months.

“The vaccine suppresses the stimulant effects of the drug,” according to Janda, co-author of a paper that appears in the Jan. 4 online edition of the journal Medical Therapy. “Unlike other types of treatment, a vaccine such as this one does not interfere with the neurological targets of the drug, but instead blocks cocaine from ever reaching the brain in the first place.”

The vaccine could be the first to offer cocaine addicts a simple way to break and reverse their habit, according to Janda. The approach could also be useful in treating other addictions, such as to nicotine, heroin and methamphetamine.

Extensive testing in humans is required before the vaccine becomes available commercially.

Related posts:

  1. Scripps Health receives grant to study electronic knee
  2. RESEARCH REPORT: Role of ‘friendship paradox’ possible in epidemics
  3. Injured people on board for Life Rolls On event
  4. National liver expert joins UCSD
  5. Scripps professor receives NIH Director's Pioneer Award

Short URL: http://www.lajollalight.com/?p=32244

Posted by Staff on Jan 4, 2011. Filed under Health & Science, News. You can follow any responses to this entry through the RSS 2.0. You can leave a response or trackback to this entry

Leave a Reply

La Jolla Community Calendar

Facebook

Bottom Buttons 1

Bottom Buttons 2

Bottom Buttons 3

Bottom Buttons 4

Bottom Buttons 5

Bottom Buttons 6

RSS North Coastal News

  • Solana Beach water district moving to mandatory water use restrictions August 22, 2014
    Customers of the Santa Fe Irrigation District — including residents of Rancho Santa Fe, Solana Beach and part of Fairbanks Ranch — will face mandatory restrictions on water use starting Sept. 5, in an effort to save water due to an ongoing statewide drought. The restrictions include a three-day-per-week watering schedule for all homes and businesses, a prohi […]
  • West Coast FC Classic Champs August 22, 2014
    Congratulations to Coach Beto Villela and the San Diego Surf BU11 Academy (Villela) team. The boys won the West Coast FC Classic Tournament last weekend, held in Mission Viejo. […]
  • Surf GU9 team takes first place in Orange County Kickoff classic August 22, 2014
    The Surf Soccer Club Academy GU9 team took first place in the 2014 Orange County Kickoff Classic (Girls U9 flight 1) on Aug. 16-17. […]